Showing posts with label telomerase. Show all posts
Showing posts with label telomerase. Show all posts

Thursday, February 14, 2013

Harvard Mice Cheat Death



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Harvard Mice Cheat Death

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Easy Health Options: Nature & Wellness Made Simple

Dear Jorge,

Please find below a special message from our friend
Al Sears M.D. He has some important information to share with you.

Sincerely,

Michael Cutler, M.D.
Editor, Easy Health Options®



Old Mice "Cheat Death"
with New Breakthrough
from Harvard Medical School
Dear Jorge,
In a landmark study that sounds like science fiction, a professor at Harvard Medical School regenerated the brains of aging mice by turning on a switch inside their cells.
Mice with telomerase
Mice with telomerase activated (left) look much younger than those that had the enzyme turned off (right).[Credit: Mariela Jaskelioff/Harvard Medical school]
The mice, who were the equivalent of elderly men, had all the classic signs of old age: Their brains were smaller... they were going blind... they stopped having sex... their hair was gray... and they couldn't find their way through a maze or remember where their food was. 
But when this Harvard professor hit the switch in their cells, the tissues and organs in their body -- including their brains -- started to regenerate and grow back to normal size.
Even a slight change in brain size would have been a miracle... but what happened was even more remarkable.
The gray hair was gone. So was the poor eyesight and shrunken brains. In fact, there was nothing left that could distinguish them as "old."¹
And here's the best part:
This "Age-Reversing Switch" Can Be Turned On in Us Too
Meet Dr. Al Sears, MD
Uniquely Qualified to
Keep You Healthier for Life
Dr searsDr. Al Sears, MD, is a medical doctor and one of the nation's first board-certified anti-aging physicians.
As a board-certified clinical nutritionist, strength coach, ACE-certified fitness trainer and author, Dr. Sears enjoys a worldwide readership and has appeared on more than 50 national radio programs, ABC News, CNN and ESPN.
In 2010, Dr. Sears unveiled his proven anti-aging strategies in Reset Your Biological Clock. As the first U.S. doctor licensed to administer a groundbreaking DNA therapy that activates the gene that regulates telomerase, Dr. Sears made history by bringing telomere biology to the general public. 
In 2006, Dr. Sears shocked the fitness world by revealing the dangers of aerobics, "cardio" and long-distance running in his book, PACE: The 12-Minute Revolution.
In 2004, Dr. Sears was one of the first doctors to document the true cause of heart disease and expose the misguided and often fatal drugs-and-surgery approach to heart health.
In The Doctor's Heart Cure, Dr. Sears outlines the easy-to-follow solution that effectively eliminates your risk of heart disease, high blood pressure and stroke.
An avid lecturer, Dr. Sears regularly speaks at conferences sponsored by the American Academy of Anti-Aging Medicine (A4M), the American College for the Advancement of Medicine (ACAM) and the Age Management Medicine Group (AMMG).
I've been researching and studying the remarkable science behind this breakthrough since it was discovered almost 20 years ago. I was the first doctor in the country licensed to administer the supplement based on this science. I've also written about it extensively and given many lectures... like the standing room only presentation I just made at the International Conference on Anti-Aging and Regenerative Medicine in Malaysia.
And as you'll see in just a moment, clinical studies confirm the effectiveness of this therapy in men and women. In fact, the discovery that led to the breakthrough won the Nobel Prize in Medicine in 2009.
That means we now have the ability to repair our own aging brains... reignite our flagging sex drives... correct our failing eyesight... and sharpen our minds as if we were 21 again.
The "switch" responsible for this dramatic reversal of aging is telomerase.
It's the enzyme that helps you rebuild the "biological clocks" at the end of your DNA called telomeres.
Today, I'm going to show you how to tap the remarkable power of your telomeres and the age-reversing enzyme that helps maintain them. That way, you can keep doing everything you want for longer than you ever thought possible.
Staying Younger Longer is Well Within Your Reach
Telomeres are the "time keepers" attached to every strand of your DNA. Each time your cells divide, your telomeres get shorter. When your telomeres become too short, cell division stops and your life ends.
By slowing down the loss of your telomeres, you not only extend your lifespan, you stay younger longer.
That's what I do for my patients. And it's important you know how this works.
As the telomere gets shorter, your body produces cells that are older, weaker and more decrepit. 
This speeding up of telomere loss actually causes your body to transcribe an older, more dysfunctional part of your genome. That means your body becomes weaker, more frail and open to all the diseases of aging.
But if you take action now you can turn back that dial and enjoy a younger body for years, maybe decades longer.
Slowing the loss of the telomere, and in some cases making the telomere longer, is how you grow "biologically younger." Regardless of your chronological age, you can enjoy the energy and physical power of someone much younger.
And that's where the story I told you earlier becomes important. It proved for the first time that telomerase reverses features of aging in a whole organism.
Harvard Professor Who "Cheated Death"
Turned On Telomerase
The study of the now-famous mice who cheated death and became "reborn" as much younger mice was published in the prestigious journal Nature.
The lead researcher Dr. Rod DePinho is a professor of genetics at Harvard Medical School and director of applied cancer science at the Boston-based Dana-Farber Cancer Institute.
When the mice had their telomerase turned on, they were rejuvenated after only one month.
Their telomeres were longer, and their telomerase levels increased. Brain cells that were dormant came back to life, producing new neurons. Their shrunken organs, like spleens and even testes and brain... grew in size.
Key organs functioned better, and the mice got their sense of smell back. The males also produced new sperm cells, and their mates gave birth to larger litters.
The mice went on to live long healthy lives.
After Dr. DePinho and his colleagues had taken mice and made them young again, he said the study produced results that were the equivalent of finding the famed fountain of youth.
And by taking a few simple, easy steps I'm going to show you that promote longer telomeres, you can recreate that fountain of youth inside your body.  
You don't have to make any radical changes.
There are no impossible, insane workouts.
No diet that will deprive you of anything.
Just a better, longer life with a dramatically lower risk of becoming sick as you get older.
Studies Show Short Telomeres
Skyrocket Your Risk of Disease
Compelling evidence shows the length of your telomeres determines your risk for many of the illnesses that come with age. For example:
  • A team at Harvard discovered that having short telomeres nearly doubled the risk for bladder cancer.²
  • The journal Breast Cancer Research and Treatment published findings that breast cancer cells had shorter telomeres than normal cells.³
  • Japanese researchers found cancers of the mouth begin in cells with short telomeres.4
  • The British Journal of Cancer reported that colon cancer cells have shorter telomeres.5
By contrast, when you have longer telomeres, your cells don't age as quickly. Not only do you avoid diseases like cancer, you live younger longer.
Have a look at these study results:
  • 100 year olds in good health had "significantly longer" telomeres than those with health problems.6
  • Your risk of heart attack increases the faster your telomeres break down. When researchers looked at people in perfect health who later died from heart disease, they found the death rate from heart attack was three times higher for men whose telomeres got short the fastest. The death rate for women was 2.3 times higher.7 Simply stated, the shorter your telomeres, the higher your risk of death from heart attack.
  • People with shorter telomeres in their immune cells had twice the risk of death from heart failure as patients with the longest telomeres. The study, published by the American Heart Association, found the highest-risk group had telomeres half the length of the lowest-risk group.8
The message here is clear. When you preserve telomere length, you preserve life and youth. 
We now understand the very mechanism by which you age. And we've found a simple system that helps you preserve your telomeres and extend your lifespan.
I'll Show You Exactly How it Works...
12 Steps to Reverse AgingIn The "Fountain of Youth" Breakthrough, you'll find simple, easy-to-understand solutions that help you grow "biologically younger," and feel years younger with maximum energy and performance.
I'll show you the only proven ways to activate telomerase in your own cells... and the telomere secrets that help you live disease-free for the rest of your life.
Here's a quick peek:
  • Forget Aerobics and Cardio... A certain type of exercise affects your telomeres, making them longer and stronger.
  • Recently a study of 2,401 twins found that physical activity was related to telomere length. Those who exercised using these principles for just 3 hours a week had telomeres that looked 9 years younger.
  • Crank UP these Nutrients...One antioxidant in particular has consistently been associated with longer telomeres in dozens of studies. Raising your level of this vitamin in your cells could slow down the loss of telomeres up to 62%.
  • I'll show you a more bio-available form of this nutrient and how much to take. Here's a hint: It's 1,011% more than the FDA recommends. Not only does it slow telomere loss, it supports heart health, immune system strength and blood vessel integrity.
  • Clean Up this "Waste Product"... There's a natural byproduct of metabolism that's safe at normal levels. But blood levels of it tend to increase with age. And when you have too much of it in your system, it wreaks havoc.
  • Researchers found that people with high levels of this amino acid tripled the amount of telomere length that was lost during cell division. That means a build up can force you to age 300% faster.
  • Clear Your Mind...A simple technique that slows down your thoughts and helps focus your mind boosts the activity of telomerase by 33%.
  • This remarkable find was proven in a clinical study at the University of California and is easy to learn. Plus it only takes 10 minutes!
  • Live Younger with this "Essential Fat"... A study in the Journal of the American Medical Association followed patients for 5 years. Those with the lowest levels of this critical "essential fat" had the fastest telomere shortening.
  • Those with the highest omega-3 levels had the slowest telomere shortening. I'll show you which fat they used, where to find it and how much to take.
Download The "Fountain of Youth" Breakthrough today and you'll discover ALL of these age-reversing secrets and so much more...

What people are saying about Dr. Sears' methods…

My pain is gone!

"I used to suffer from such bad leg, back, and hip pain that I had trouble getting out of bed in the morning. I used to ask my wife to pull on my legs so that I could get up. I had trouble standing on my feet all day and walking long distances. I used to dread winter. The cold air would make the pain worse. My mother had hip surgery and I was worried that I might have to have surgery too. I came to Dr. Sears. Now, my pain is gone. I own a restaurant, so I'm on my feet all day. I'm able to work long hours without pain. My grandkids have to keep up with me now! "
– Louis F., Wellington, FL

I used to take 18 pills a day…

"I was disabled for 14 years. Doctors had told me that I had 10 different conditions. I was taking 18 pills a day. I was told by the doctors that I would have to be in a wheelchair and take oxygen for the rest of my life. I would go 3 to 4 days without sleep.
"I came to Dr. Sears with the goal of getting off my medications. He helped me to cut my medications. He also took the time to educate me and explain the basics of health and nutrition. Today, I feel great. I can sleep at night. I'm no longer bloated or irritable. I no longer take all of the medications I used to."
– Francine C.

Never thought I could feel
this good

"I injured my back in the military in 1970. After several operations it got worse and my inactivity brought on diabetes in 2000. With it came high cholesterol, weight gain, difficulty breathing, high BP and inability to go up a flight of stairs. I stopped taking many of my meds and trusted your supplements instead. Now I walk 2.2 km once or twice a day. I never thought I could feel this good again. Thank you."
—Dan B.

My fatigue is gone – I feel alive!

"I talked to Dr. Sears to get help with high cholesterol. Other doctors had put me on several different cholesterol medications and statin drugs over the years. Those drugs left me with severe muscle pain and I was tired all the time. Dr. Sears made me aware of the various dangers of cholesterol medications and showed me safe and natural methods of lowering cholesterol and maintaining a healthy heart.
"Where Dr. Sears took the time to educate me on the important facts, other doctors just wrote me a prescription and sent me on my way. Now, I'm taking two all-natural supplements and sticking to his diet suggestions. My fatigue and muscle aches are completely gone. For the first time, I feel alive! And I feel like I'm doing a service for my body."
—Penny O.
Hundreds of people paid $29.95 for The "Fountain of Youth" Breakthrough, but I'd like to give it to you FREE…
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No matter how you're feeling right now, there is something you can do to live better and feel younger.
In fact, on my recent trip to Africa, I found an incredible number of healing secrets almost unknown in the West. The healers there showed me what they use to successfully treat prostate and breast cancer.
I've seen the most amazing pictures of people half eaten up with cancer – and in the next photo, you can see they've been healed. A lesion on a woman's breast almost gone in 4 days. Skin cancer healed, prostate cancer gone...
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  • How to get rid of the amino acid that doubles your risk for Alzheimer's.
  • The keys to defending your brain from toxins in the modern world
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To Your Good Health,

Al Sears, MD
P.S. Remember those old mice I told you about who were "cheating" their way through Harvard medical school? They rediscovered their youth with the same age-reversing enzyme that has been transforming the lives of my patients. Now it's your turn to experience this incredible discovery for yourself. Activate your membership in Confidential Cures right away and I'll rush you all the details you need to start living younger, now.
Check MarkYes, Dr. Sears! I want to live younger, starting today! Please begin my membership in Confidential Cures: Your Guide to Truth and Lies in Medicine from Around the World for just $39 and deliver my 5 FREE Bonus Reports, including The "Fountain of Youth" Breakthrough. I'll be able to download my exclusive Bonus Reports right away – absolutely FREE! That's a total savings of $110.82! I understand my satisfaction is FULLY guaranteed.
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1 Horner J, Maratos-Flier E, Depinho R, et. al. "Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice." Nature. 2011 Jan 6;469(7328):102-6.
2 McGrath M, et al. "Telomere length, cigarette smoking, and bladder cancer risk in men and women." Cancer Epidemiol Biomarkers Prev. 2007 Apr;16(4):815-9.
3 Diehl MC, et al. "Elevated TRF2 in advanced breast cancers with short telomeres." Breast Cancer Res Treat. 2010 Jul 13.
4 Aida J, et al. "Telomere lengths in the oral epithelia with and without carcinoma." Eur J Cancer. 2010 Jan;46(2):430-8.
5 Rampazzo E, et al. "Relationship between telomere shortening, genetic instability, and site of tumor origin in colorectal cancers." Br J Cancer. 2010 Apr 13;102(8):1300-5.
6 Delara et al. "Association of Longer Telomeres With Better Health in Centenarians." The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 208. 63:809-812.
7 Delude, C. "Genetic clues to predicting life span: Inside chromosomes are telomeres that age as we age, and may serve as indicators of how long we'll live." Los Angeles Times. March 2, 2009. Retrieved July 6th, 2012.
8 Farzaneh-Fal et al. "Prognostic Value of Leukocyte Telomere Length in Patients With Stable Coronary Artery Disease: Data From the Heart and Soul Study." Arteriosclerosis, Thrombosis & Vascular Biology. 2008. 28(7):1379-1384.

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Wednesday, January 16, 2013

How Switching on a Certain Enzyme Can Help You Live Longer and Healthier



---------- Forwarded message ----------
From: Underground Health Reporter <info@1minutecure.com>
Date: Mon, Jan 14, 2013 at 8:00 PM
Subject: How Switching on a Certain Enzyme Can Help You Live Longer and Healthier




Brought to you by Think-Outside-the-Book Publishing, LLC
How Switching on a Certain Enzyme Can Help You Live Longer and Healthier

In This Issue:

*Did You Know...?
*Featured Article: How Some People Live to the Age of 100, 122, or Even 150 Years Old
*A Word from Our Sponsor:
Breakthrough Natural Remedies Stop Acid Reflux In Its Tracks

Did You Know...

...you could be slowly poisoning yourself while you sleep?

     To be well rested, you should spend about 1/3 of your life sleeping.  However, once you know what's inside your mattress, you may find that hard to do.  In order to comply with nationwide fire safety standards—developed from an earlier California law (which I'll explain further in a moment)—manufacturers coat their mattresses in flame-retardant chemicals known to cause cancer and nervous system disorders.

     Top companies such as Simmons, Sealy, and Tempur-Pedic refuse to divulge the exact composition of the chemical blend they use, as they claim the formulas are trade secrets.  So Walter Bader, owner of the "green mattress" company Lifekind and author of Toxic Bedrooms, took matters into his own hands.

     Bader sent several different types of mattresses to an Atlanta-based lab to be tested.  The results showed that a single memory-foam mattress emitted 61 chemicals, including benzene and naphthalene, known carcinogens.

No Level of Exposure is Safe

A risk assessment conducted by the Consumer Product Safety Commission (CPSC) found that each night, the average adult absorbs .802 mg of antimony and .081 of boric acidboth are acutely toxic.  The CPSC itself acknowledges that the carcinogenic effect of antimony is cumulative: "Every exposure contributes to the overall lifetime risk of developing cancer."

     According to the Center for Disease Control (CDC), there is no level of exposure to antimony that is safe: "At the lowest exposure levels tested, the adversity of the effects was considered to be serious."

     Boric acid is also a popular roach killer.  Its known effects on humans include:

  • Reduced sexual activity
  • Infertility
  • Birth defects
  • Sterility
  • Death

Fireproof, and "Toxic to Humans"

Whitney Davis, who wrote the original California law, is now having serious second thoughts about the fire safety guidelines he initially championed.  "The problem: the only chemicals they can use to achieve compliance are listed as toxic to humans by the EPA, "he said.  "You don't know until 10 years down the road [that] there's a problem.  We feel responsible."

     Mattress industry insiders say they expect backlash as consumers begin to investigate "what's really lying under their sheets with them."  That backlash may arrive soon: workers are now coming forward with stories about how simply handling the chemically laden mattresses has made them sick.

How to Sleep Chemical Free

While the fire safety laws are well intentioned, the odds of someone dying in a mattress fire are close to 1 in a million.  The risk posed by nightly exposure to toxins is far more pressing.

     Until existing fire safety laws are amended, experts say your best option is to shop around and find a toxin-free mattress.  There are many options out there—from latex to wool.  It's even possible for a doctor or a chiropractor to prescribe a toxin-free bed.  As an added bonus, prescription mattresses are tax deductible!

= = = = = = = = = = =

Featured Article:
How Some People Live to the Age of
100, 122, or Even 150 Years Old

Advancements in medicine and technology have allowed us to stretch the limits of our maximum life span, and some scientists now believe it is possible to lengthen that span to 150 years and beyond.

     How would you like to live to the age of 100 ... or 122 ... or even 150 years?

     There is one major thing that limits the average human lifespan to 79 years old—and that is an enzyme discovered by a Nobel Prize winning scientist.  This enzyme acts as a buffer against aging and regenerates lost youth by acting as your immortality switch—and lack of it causes just the opposite.

     Now, there are many ways to turn on that switch in order to increase your probability of reaching the century mark—and you can learn them for f*r*e*e when you read further.

How Do We Age?

Cells are the building blocks of life, and our bodies are filled with trillions of them.  In each of these cells lies a nucleus and inside the nucleus are chromosomes, which contain our genes.  Every chromosome has two arms, each made up of a single molecule of DNA.  A DNA molecule starts life 100 million bases long, and at its tip are end caps called telomeres.

     Our DNA strands are about 15,000 bases long when we are in the womb.  As soon as we are born, however, our cells begin to divide in order to get nutrients into, and waste products out of, the nucleus.  Every time a cell splits, the telomeres become shorter.  Once your telomeres are made up of only 5000 bases, you die, if not from disease, then from old age itself.

Telomeres: The Key to Longevity

Over 1,000 studies have linked shortened telomeres to aging and disease.  Shorter telomeres have also been linked to health problems such as:


    Cancer, particularly of the bladder, mouth, breast and colon
    Weakened immune system and a greater susceptibility to infections
    Neurodegenerative diseases like Parkinson's and Alzheimer's
    Type 2 Diabetes
    Atrophy of the spleen, intestines and testicles
    Atherosclerosis
    DNA damage

In 1984 biochemist and biophysicist Elizabeth Blackburn discovered that the enzyme telomerase can actually lengthen telomeres.  In 2009 Blackburn, along with Carol Greider and Jack Szostack, was awarded the Nobel prize for revealing that chromosomes are protected by telomeres and telomerase.

     Telomerase protects your cells and your health by slamming the brakes on telomere shortening and activating the switch that lengthens and rebuilds them.  Numerous animal studies have shown that chronic health conditions can be reversed by switching on this enzyme.

Lifestyle Choices for an Ageless Body and Mind

Dr. Al Sears M.D., the first physician in America licensed to administer the supplement based on telomere-therapy, has compiled a comprehensive handbook that presents lifestyle choices that help lengthen your telomeres and increase your longevity.  In this f*r*e*e guide, Dr. Sears reveals:

  • the key nutrients to activate telomerase (and the best way to get them);
  • a quick and easy technique that helps slow down your thoughts and sharpen your focus, thereby contributing to anti-aging;
  • a very simple (but effective!) anti-aging workout that caused the subjects in a telomere study involving twins to be a decade younger than those of their inactive siblings.

      Due to overwhelming response, Dr. Al Sears has extended his offering of this handbook titled The Fountain of Youth Breakthrough.  This free guide offers easy-to-understand solutions to turn on the telomerase switch in your cells and live a disease-free life well into your century mark.

      Click here now and learn about a landmark Harvard study involving test mice with all the signs of old age (smaller brains, failing eyesight, low libido, gray hair, poor memory and cognitive skills), who experienced tremendous age reversal.  They had significant brain regeneration—and their gray hair, poor eyesight and all signs of aging disappeared when the immortality switch was turned on.  Find out how this age-reversing switch can be turned on in you, too, by going here.



If the link above isn't working, just copy & paste the following
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--
Jorge U. Saguinsin
To "be the best, do your best, expect the best" always