Saturday, April 18, 2020

Drugs being investigated for treatment vs. Covid 19

Live healthy and long

Rizal Philippines
April 18, 2020


Immunometabolism Network on Twitter: "What is hydroxychloroqine ...


From Livescience - drugs vs Coronavirus being investigated

There are quite a number:


Emory's DRIVE, Ridgeback partnering for drug vs coronavirus ...

1.  EIDD 2081 published in Science Transnational Medicine can be an oral medicine just  like Tamiflu. Unlike remdesivir (given by injection) which kills virus entirely, EIDD introduces mutation into the RNA of the virus so that it stops reproducing itself.  The drug has been licensed by Ridgeback Biotherapeutics Florida based, and has obtained license  for clinical trials

Avigan: Antiviral being tested for coronavirus patients - Health ...




Fujifilm announces the start of a phase III clinical trial of ...

2.  Japan Anti Flu Drug -   Avigan (Favipiravir)  was an anti flu drug made by FujiFilm Pharmaceutical and works with mild to moderate  cases and was shown to be effective in 340 cases in Wuhan China.  However, of late, because of disruption in supply chain, Japan would not be able to cope up with the demand.

The drug prevents certain virus from replicating  and improves lung condition (Dr. Sultan reports that the action of favirapir is to disrupt the Corana virus from detaching the iron form the haema by competing with the same at the cell surface


3.  Chloroquine and hydroxycholoroquine

It works by blocking the aibility of the virus to enter into human cell and replicate.  (In our theory that it a blood disease, the medication competes with the virus from removing the iron from haeme.) The corona hairs from  reaching the ACE of the the cells  (see first picture)  Its efficacy was seen in anectdotal reports from France.   Pres Trump and Ellon Musk praised the drug to the heavens.  Its side effect, being toxic, however made some Euro countries dump the medication.  India banned the export of the drug, the country itself facing crisis with covid 19


Risks of Antihypertensive drugs with COVID-19 | Physician's Weekly


Image 1




4. Anti hypertensive drug.       Losartan it is an angiotensin receptor inhibitor and used mainly to reduce high blood pressure.  And works well when the covid 19 patient is hypertensive.   As an ACE inhibitor it may work to prevent the virus from attaching to the cell and multiplying.    Losartan is included in the protocol for treating coVid Patients (to lessen virus overload)   Persons whom we know of who were in Chinatown during Chinese New Year and who were on Losartan, and who developed the symptoms got better and were cured...

5.  Failed Ebola drug -  remdesivir. It is given to compassionate cases - ie those who are hopeless. However there has been a deluge of compassionate case and the said use is stopped.

6.  A combination HIV drug  Kaletra;  however the results of the trial was not conclusive, statistically significant.

7.  To counter auto immuno reaction  - cytokine reaction when the body overcome by infection goes into overdrive and attacks its own cells like in Lupus or arthritis. -  Actemra or tocolizumab. Mechanism of action it blocks cell receptor of Interlukine 6, a cytokine a protein that causes dangerous immune system reaction



USTC Global on Twitter: "The mechanism of using Tocilizumab to ...

The supportive treatment are Vitamin C, corticosteroid,  high flow oxygen,, and Zinc.

Maybe if we have zinc, we have people on Losartan, or safe ACE inhibitor we do not need the expensive vaccine they are developing (especially the the onebBill Gates Foundation is developing) as preventive  meds.  Those who are ill can be on Avigan.  

Is it now accepted that after preventing the findings of East Virginia, Dr. Sharif, that coVid19 is a cellular level oxygenation disease rather than a system respiratory disease?

For the former, we need more of hyperbaric chamber, blood transfusion, plasma pheresis (use of dialysis machine) and less of Ventilators and intubation.   Intubation is a dangerous procedure that infects the medical  practitioner and injures the patient...

N.B. The blogger  merely researches article and does not pretend to be a medical expert.   However, the articles are well referenced

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