Monday, April 28, 2014

Carbonated drinks lead to elevated uric acid level

Live healthy and long

Rizal Philippines  | April 28, 2014

From Carbonated drinks com

 

Ever wondered how come some people do not eat food that are high in purines like meat, poultry, fish, beans, and yet have elevated uric acid level.  I was at a loss when I was asked by neighbors about this.

This post is a Eureka.  High consumption of softdrinks  can cause elevated uric acid level;    " It may be a factor responsible for the elevated levels of uric acid in the blood stream. Elevated levels may also lead to deposition of uric acid crystals in joints, tendons and surrounding tissues"

So guys slow down on your cola drink consumption.  When you have high uric acid level or goes up, you know the answer.

It can be caused also by high level of alcohol or beer intake



Gout Triggers, Risk Factors and Effects of Beer and Other Alcohol

Gout Risk Factors

Gout is associated with several other disorders, including high blood pressure and heart disease. It is important to receive prompt diagnosis, and to manage these conditions. Adopting lifestyle and diet changes, as well as revisiting any medications you are taking for other disorders, can make a significant difference in patients with milder cases of gout.
The following are cumulative risk factors for gout:
  • Obesity – defined as a Body Mass Index (BMI) of 30 or higher. Click here to calculate your BMI.
  • Untreated high blood pressure, diabetes or high cholesterol
  • High levels of serum triglycerides in the blood, which are associated with an increased risk of heart disease
  • Joint injury – urate crystals are more likely to form in a joint that was previously damaged and/or a recent injury can bring on a gout attack
  • Diuretics – when taken by people with high blood pressure, leg swelling or heart failure, diuretics can decrease the kidney’s ability to remove uric acid and result in hyperuricemia
  • Chemotherapy – the breakdown and turnover of cells leads to an increase in uric acid
  • Kidney disease – when the kidneys are not working as a filter at 100 percent capacity, they cannot remove enough excess uric acid, leading to hyperuricemia
  • Genetics – fact: one out of four people with gout have a family history of the condition
  • Hyperuricemia – elevated uric acid levels can cause gout to flare up
  • Cyclosporine – Taking this anti-rejection transplant medication
  • High fructose intake

Gout Triggers

Gout triggers are usually different from one person to another. Many patients find their gout easier to manage once they determine their specific triggers. Keeping a lifestyle diary may help you determine what foods, beverages or activities can cause your gout to flare.
Certain uric acid lowering medications can also cause gout to flare initially. It is important to ask your doctor about this side effect, and to continue taking the medication as directed through the flare.
  • Regular, excessive alcohol intake, especially beer or binge drinking
  • Surgery or a sudden, severe illness for which you are bedridden
  • Consuming large quantities of purine-rich foods, especially red meat, organ meat and shellfish
  • Radiation therapy
  • Crash diets, especially high-protein fad diets
  • A diet high in fructose, including soft drinks and fruit juices
  • Starting a uric acid-lowering treatment medicine (even though it may be the correct long-term therapy)

Gout and Alcohol

Regular, excessive alcohol intake, especially beer or binge drinking, may cause gout to flare up.

Copyright © 2009 Gout & Uric Acid Education Society

From Sunwarrior





Taking alcohol and sugary drinks aside from eating meat products and other food rich in (purines) protein:



by Jennifer Novakovich
gout_a_growing_concern_imageGout is the most common form of arthritis in men over the age of 40 and was reported, in 2008, to affect over 8.3 million people in the United States. It is likely one of the oldest diseases and has even been observed in dinosaur bones. But it was first recognized by the Egyptians in 2640 BC. The disease is characterized by reoccurring episodes of extremely painful joint inflammation, caused by monosodium urate crystal deposits. Do you or someone you know have gout? Or are you concerned about developing gout in the future? Read on for more information about this painful disease.
Gout has markedly increased over the past few decades in parallel to the rise in obesity. In fact, more than 60% of individuals with gout have or later develop metabolic syndrome. Elevated uric acid levels, a precursor for gout, are associated with many other chronic diseases including diabetes, heart disease, hypertension, renal dysfunction, and obesity. For every 1mg of blood urate that is increased, there is a 13% heightened risk for hypertension!
Like I said before, higher levels of blood uric acid is a precursor for gout. So what is uric acid? Uric acid is a waste product of purines (e.g. adenosine, adenine, guanine) in the body following metabolism; it is our main fat soluble antioxidant, responsible for as much as two-thirds of our total antioxidant capacity. While short term increases in blood uric acid provide protection against oxidative stress, long term increases are associated with not only gout, but most chronic diseases. 
sugary_soft_drinks_increase_risk_for_gout_picAgain, increased blood uric acid content is thought to be an attempt for protection against oxidative stress. Risk factors for higher uric acid include a higher weight and body fat percentage with lower muscle mass as well as the consumption of meat (especially red meat), seafood, aspirin, diuretics, alcohol and sugary foods. Drinking alcohol, at intakes higher than 15g/day, results in a 93% higher risk of gout. Risks are significantly raised by drinking as little as 10-14.9g/day. Beer has been associated with 2.5 times higher risk while liquor is 1.6 times higher (risks don’t seem to be elevated through red wine consumption). Every additional meat serving per day leads to a 21% higher risk while seafood leads to a 7% higher risk. Lastly, daily consumption of sugary soft drinks increases risks for gout by 85%.
Most people with elevated blood uric acid never end up with gout, but for those who do, it usually happens by around 40–60 years of age in men and 65 in women. Males are over twice as likely to develop gout than females. Heightened uric acid in the blood can eventually lead to the formation of monosodium urate crystals, which are deposited in tissue. Eventually those deposits can lead to first acute gout—with little to no symptoms between gout attacks—and then, when not adequately treated, chronic gout—with symptoms between attacks and the formation of painful deformities. Acute gout usually begins in one joint in a lower limb and an attack results in a red, warm, swollen, and extremely painful joint. Gout is often a debilitating disease that significantly reduces the quality of life for those affected.
The goal in gout treatment is to lower blood urate levels and to dissolve urate crystals. Traditionally, on a pharmacological basis, acute gout is often managed with nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine, or glucocorticosteroids, while chronic gout is managed with urate-lowering therapy such as allopurinol, febuxostat, probenecid and sulfinpyrazone. Unfortunately for many, medical treatment for gout is often insufficient, and as a result individuals affected have little to no relief from gout symptoms and the development of the disease to chronic gout. Lifestyle interventions are an important component for the management of gout but unfortunately due to many factors (i.e. many doctors have little to no background in nutrition), patients are often not exposed to these recommendations.
cherries_reduce_blood_uric_acid_levels_imageWhat lifestyle interventions help manage gout? Exercise, weight loss, and also higher vegetable, nut, legume, coffee, and vitamin C consumption is associated with lower blood uric acid. Risks for gout are seen to be 40% lower with 4–5 cups of coffee a day. 1500 mg/day of vitamin C, in a supplemental form, is associated with a 45% decreased risk for elevated blood uric acid. Growing research is accumulating in the role of cherries, with their high vitamin C content, in the management of gout. Eating two servings of cherries a day is seen to significantly reduce blood uric acid, inflammation, and the number of gout attacks. There has been positive results with tart cherry juice concentrate in several small studies for the management of gout, but currently more research is needed to strengthen the validity of this treatment option. Purine-rich vegetables, nuts, legumes, and vegetable protein, despite their purine content, are not associated with gout. Furthermore, people who eat more vegetable protein have a 27% lower risk for developing gout.
So how can you take this information and apply it to yourself? First things first, you’ll have to reduce things that are seen to elevate blood uric acid. Try to reduce (or eliminate) meat (especially red meat), alcohol (beer and liquor, wine can stay!), and sugary foods. Reducing fish consumption may also be a good idea but the heart protective components of fish should be considered (especially since gout increases risks for heart disease). A DHA based omega-3 supplement should be strongly considered, especially if you are to remove fish. And now, what to add…. Exercise! If you’ve previously led a very sedentary lifestyle, start small. Find something you enjoy so that you’ll stick to it. Enrolling in a fitness class or finding a workout buddy is also another way to keep motivated. Most colleges have lots of fun workout classes—my personal favorite is aquafit! Eat more vegetables, nuts, cherries, and legumes and keep on drinking your coffee. Vitamin C supplements may also be a good addition. If you have gout and have had little relief from medical treatment, a tart cherry juice concentrate may be something good to try.
And that marks the end of my article, hopefully you now have a better idea of how to prevent and manage gout!
- See more at: http://www.sunwarrior.com/news/gout-a-growing-concern/#sthash.HxP6vFh7.dpuf


Gout: A Growing Concern

Friday, March 15, 2013 @ 05:03 AM Jennifer Novakovich
5.00/5 (100.00%) 1 vote
by Jennifer Novakovich
gout_a_growing_concern_imageGout is the most common form of arthritis in men over the age of 40 and was reported, in 2008, to affect over 8.3 million people in the United States. It is likely one of the oldest diseases and has even been observed in dinosaur bones. But it was first recognized by the Egyptians in 2640 BC. The disease is characterized by reoccurring episodes of extremely painful joint inflammation, caused by monosodium urate crystal deposits. Do you or someone you know have gout? Or are you concerned about developing gout in the future? Read on for more information about this painful disease.
Gout has markedly increased over the past few decades in parallel to the rise in obesity. In fact, more than 60% of individuals with gout have or later develop metabolic syndrome. Elevated uric acid levels, a precursor for gout, are associated with many other chronic diseases including diabetes, heart disease, hypertension, renal dysfunction, and obesity. For every 1mg of blood urate that is increased, there is a 13% heightened risk for hypertension!
Like I said before, higher levels of blood uric acid is a precursor for gout. So what is uric acid? Uric acid is a waste product of purines (e.g. adenosine, adenine, guanine) in the body following metabolism; it is our main fat soluble antioxidant, responsible for as much as two-thirds of our total antioxidant capacity. While short term increases in blood uric acid provide protection against oxidative stress, long term increases are associated with not only gout, but most chronic diseases. 
sugary_soft_drinks_increase_risk_for_gout_picAgain, increased blood uric acid content is thought to be an attempt for protection against oxidative stress. Risk factors for higher uric acid include a higher weight and body fat percentage with lower muscle mass as well as the consumption of meat (especially red meat), seafood, aspirin, diuretics, alcohol and sugary foods. Drinking alcohol, at intakes higher than 15g/day, results in a 93% higher risk of gout. Risks are significantly raised by drinking as little as 10-14.9g/day. Beer has been associated with 2.5 times higher risk while liquor is 1.6 times higher (risks don’t seem to be elevated through red wine consumption). Every additional meat serving per day leads to a 21% higher risk while seafood leads to a 7% higher risk. Lastly, daily consumption of sugary soft drinks increases risks for gout by 85%.
Most people with elevated blood uric acid never end up with gout, but for those who do, it usually happens by around 40–60 years of age in men and 65 in women. Males are over twice as likely to develop gout than females. Heightened uric acid in the blood can eventually lead to the formation of monosodium urate crystals, which are deposited in tissue. Eventually those deposits can lead to first acute gout—with little to no symptoms between gout attacks—and then, when not adequately treated, chronic gout—with symptoms between attacks and the formation of painful deformities. Acute gout usually begins in one joint in a lower limb and an attack results in a red, warm, swollen, and extremely painful joint. Gout is often a debilitating disease that significantly reduces the quality of life for those affected.
The goal in gout treatment is to lower blood urate levels and to dissolve urate crystals. Traditionally, on a pharmacological basis, acute gout is often managed with nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine, or glucocorticosteroids, while chronic gout is managed with urate-lowering therapy such as allopurinol, febuxostat, probenecid and sulfinpyrazone. Unfortunately for many, medical treatment for gout is often insufficient, and as a result individuals affected have little to no relief from gout symptoms and the development of the disease to chronic gout. Lifestyle interventions are an important component for the management of gout but unfortunately due to many factors (i.e. many doctors have little to no background in nutrition), patients are often not exposed to these recommendations.
cherries_reduce_blood_uric_acid_levels_imageWhat lifestyle interventions help manage gout? Exercise, weight loss, and also higher vegetable, nut, legume, coffee, and vitamin C consumption is associated with lower blood uric acid. Risks for gout are seen to be 40% lower with 4–5 cups of coffee a day. 1500 mg/day of vitamin C, in a supplemental form, is associated with a 45% decreased risk for elevated blood uric acid. Growing research is accumulating in the role of cherries, with their high vitamin C content, in the management of gout. Eating two servings of cherries a day is seen to significantly reduce blood uric acid, inflammation, and the number of gout attacks. There has been positive results with tart cherry juice concentrate in several small studies for the management of gout, but currently more research is needed to strengthen the validity of this treatment option. Purine-rich vegetables, nuts, legumes, and vegetable protein, despite their purine content, are not associated with gout. Furthermore, people who eat more vegetable protein have a 27% lower risk for developing gout.
So how can you take this information and apply it to yourself? First things first, you’ll have to reduce things that are seen to elevate blood uric acid. Try to reduce (or eliminate) meat (especially red meat), alcohol (beer and liquor, wine can stay!), and sugary foods. Reducing fish consumption may also be a good idea but the heart protective components of fish should be considered (especially since gout increases risks for heart disease). A DHA based omega-3 supplement should be strongly considered, especially if you are to remove fish. And now, what to add…. Exercise! If you’ve previously led a very sedentary lifestyle, start small. Find something you enjoy so that you’ll stick to it. Enrolling in a fitness class or finding a workout buddy is also another way to keep motivated. Most colleges have lots of fun workout classes—my personal favorite is aquafit! Eat more vegetables, nuts, cherries, and legumes and keep on drinking your coffee. Vitamin C supplements may also be a good addition. If you have gout and have had little relief from medical treatment, a tart cherry juice concentrate may be something good to try.
And that marks the end of my article, hopefully you now have a better idea of how to prevent and manage gout!
- See more at: http://www.sunwarrior.com/news/gout-a-growing-concern/#sthash.HxP6vFh7.dpuf

Gout: A Growing Concern

Friday, March 15, 2013 @ 05:03 AM Jennifer Novakovich
5.00/5 (100.00%) 1 vote
by Jennifer Novakovich
gout_a_growing_concern_imageGout is the most common form of arthritis in men over the age of 40 and was reported, in 2008, to affect over 8.3 million people in the United States. It is likely one of the oldest diseases and has even been observed in dinosaur bones. But it was first recognized by the Egyptians in 2640 BC. The disease is characterized by reoccurring episodes of extremely painful joint inflammation, caused by monosodium urate crystal deposits. Do you or someone you know have gout? Or are you concerned about developing gout in the future? Read on for more information about this painful disease.
Gout has markedly increased over the past few decades in parallel to the rise in obesity. In fact, more than 60% of individuals with gout have or later develop metabolic syndrome. Elevated uric acid levels, a precursor for gout, are associated with many other chronic diseases including diabetes, heart disease, hypertension, renal dysfunction, and obesity. For every 1mg of blood urate that is increased, there is a 13% heightened risk for hypertension!
Like I said before, higher levels of blood uric acid is a precursor for gout. So what is uric acid? Uric acid is a waste product of purines (e.g. adenosine, adenine, guanine) in the body following metabolism; it is our main fat soluble antioxidant, responsible for as much as two-thirds of our total antioxidant capacity. While short term increases in blood uric acid provide protection against oxidative stress, long term increases are associated with not only gout, but most chronic diseases. 
sugary_soft_drinks_increase_risk_for_gout_picAgain, increased blood uric acid content is thought to be an attempt for protection against oxidative stress. Risk factors for higher uric acid include a higher weight and body fat percentage with lower muscle mass as well as the consumption of meat (especially red meat), seafood, aspirin, diuretics, alcohol and sugary foods. Drinking alcohol, at intakes higher than 15g/day, results in a 93% higher risk of gout. Risks are significantly raised by drinking as little as 10-14.9g/day. Beer has been associated with 2.5 times higher risk while liquor is 1.6 times higher (risks don’t seem to be elevated through red wine consumption). Every additional meat serving per day leads to a 21% higher risk while seafood leads to a 7% higher risk. Lastly, daily consumption of sugary soft drinks increases risks for gout by 85%.
Most people with elevated blood uric acid never end up with gout, but for those who do, it usually happens by around 40–60 years of age in men and 65 in women. Males are over twice as likely to develop gout than females. Heightened uric acid in the blood can eventually lead to the formation of monosodium urate crystals, which are deposited in tissue. Eventually those deposits can lead to first acute gout—with little to no symptoms between gout attacks—and then, when not adequately treated, chronic gout—with symptoms between attacks and the formation of painful deformities. Acute gout usually begins in one joint in a lower limb and an attack results in a red, warm, swollen, and extremely painful joint. Gout is often a debilitating disease that significantly reduces the quality of life for those affected.
The goal in gout treatment is to lower blood urate levels and to dissolve urate crystals. Traditionally, on a pharmacological basis, acute gout is often managed with nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine, or glucocorticosteroids, while chronic gout is managed with urate-lowering therapy such as allopurinol, febuxostat, probenecid and sulfinpyrazone. Unfortunately for many, medical treatment for gout is often insufficient, and as a result individuals affected have little to no relief from gout symptoms and the development of the disease to chronic gout. Lifestyle interventions are an important component for the management of gout but unfortunately due to many factors (i.e. many doctors have little to no background in nutrition), patients are often not exposed to these recommendations.
cherries_reduce_blood_uric_acid_levels_imageWhat lifestyle interventions help manage gout? Exercise, weight loss, and also higher vegetable, nut, legume, coffee, and vitamin C consumption is associated with lower blood uric acid. Risks for gout are seen to be 40% lower with 4–5 cups of coffee a day. 1500 mg/day of vitamin C, in a supplemental form, is associated with a 45% decreased risk for elevated blood uric acid. Growing research is accumulating in the role of cherries, with their high vitamin C content, in the management of gout. Eating two servings of cherries a day is seen to significantly reduce blood uric acid, inflammation, and the number of gout attacks. There has been positive results with tart cherry juice concentrate in several small studies for the management of gout, but currently more research is needed to strengthen the validity of this treatment option. Purine-rich vegetables, nuts, legumes, and vegetable protein, despite their purine content, are not associated with gout. Furthermore, people who eat more vegetable protein have a 27% lower risk for developing gout.
So how can you take this information and apply it to yourself? First things first, you’ll have to reduce things that are seen to elevate blood uric acid. Try to reduce (or eliminate) meat (especially red meat), alcohol (beer and liquor, wine can stay!), and sugary foods. Reducing fish consumption may also be a good idea but the heart protective components of fish should be considered (especially since gout increases risks for heart disease). A DHA based omega-3 supplement should be strongly considered, especially if you are to remove fish. And now, what to add…. Exercise! If you’ve previously led a very sedentary lifestyle, start small. Find something you enjoy so that you’ll stick to it. Enrolling in a fitness class or finding a workout buddy is also another way to keep motivated. Most colleges have lots of fun workout classes—my personal favorite is aquafit! Eat more vegetables, nuts, cherries, and legumes and keep on drinking your coffee. Vitamin C supplements may also be a good addition. If you have gout and have had little relief from medical treatment, a tart cherry juice concentrate may be something good to try.
And that marks the end of my article, hopefully you now have a better idea of how to prevent and manage gout!
- See more at: http://www.sunwarrior.com/news/gout-a-growing-concern/#sthash.HxP6vFh7.dpuf

Gout: A Growing Concern

Friday, March 15, 2013 @ 05:03 AM Jennifer Novakovich
5.00/5 (100.00%) 1 vote
by Jennifer Novakovich
gout_a_growing_concern_imageGout is the most common form of arthritis in men over the age of 40 and was reported, in 2008, to affect over 8.3 million people in the United States. It is likely one of the oldest diseases and has even been observed in dinosaur bones. But it was first recognized by the Egyptians in 2640 BC. The disease is characterized by reoccurring episodes of extremely painful joint inflammation, caused by monosodium urate crystal deposits. Do you or someone you know have gout? Or are you concerned about developing gout in the future? Read on for more information about this painful disease.
Gout has markedly increased over the past few decades in parallel to the rise in obesity. In fact, more than 60% of individuals with gout have or later develop metabolic syndrome. Elevated uric acid levels, a precursor for gout, are associated with many other chronic diseases including diabetes, heart disease, hypertension, renal dysfunction, and obesity. For every 1mg of blood urate that is increased, there is a 13% heightened risk for hypertension!
Like I said before, higher levels of blood uric acid is a precursor for gout. So what is uric acid? Uric acid is a waste product of purines (e.g. adenosine, adenine, guanine) in the body following metabolism; it is our main fat soluble antioxidant, responsible for as much as two-thirds of our total antioxidant capacity. While short term increases in blood uric acid provide protection against oxidative stress, long term increases are associated with not only gout, but most chronic diseases. 
sugary_soft_drinks_increase_risk_for_gout_picAgain, increased blood uric acid content is thought to be an attempt for protection against oxidative stress. Risk factors for higher uric acid include a higher weight and body fat percentage with lower muscle mass as well as the consumption of meat (especially red meat), seafood, aspirin, diuretics, alcohol and sugary foods. Drinking alcohol, at intakes higher than 15g/day, results in a 93% higher risk of gout. Risks are significantly raised by drinking as little as 10-14.9g/day. Beer has been associated with 2.5 times higher risk while liquor is 1.6 times higher (risks don’t seem to be elevated through red wine consumption). Every additional meat serving per day leads to a 21% higher risk while seafood leads to a 7% higher risk. Lastly, daily consumption of sugary soft drinks increases risks for gout by 85%.
Most people with elevated blood uric acid never end up with gout, but for those who do, it usually happens by around 40–60 years of age in men and 65 in women. Males are over twice as likely to develop gout than females. Heightened uric acid in the blood can eventually lead to the formation of monosodium urate crystals, which are deposited in tissue. Eventually those deposits can lead to first acute gout—with little to no symptoms between gout attacks—and then, when not adequately treated, chronic gout—with symptoms between attacks and the formation of painful deformities. Acute gout usually begins in one joint in a lower limb and an attack results in a red, warm, swollen, and extremely painful joint. Gout is often a debilitating disease that significantly reduces the quality of life for those affected.
The goal in gout treatment is to lower blood urate levels and to dissolve urate crystals. Traditionally, on a pharmacological basis, acute gout is often managed with nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine, or glucocorticosteroids, while chronic gout is managed with urate-lowering therapy such as allopurinol, febuxostat, probenecid and sulfinpyrazone. Unfortunately for many, medical treatment for gout is often insufficient, and as a result individuals affected have little to no relief from gout symptoms and the development of the disease to chronic gout. Lifestyle interventions are an important component for the management of gout but unfortunately due to many factors (i.e. many doctors have little to no background in nutrition), patients are often not exposed to these recommendations.
cherries_reduce_blood_uric_acid_levels_imageWhat lifestyle interventions help manage gout? Exercise, weight loss, and also higher vegetable, nut, legume, coffee, and vitamin C consumption is associated with lower blood uric acid. Risks for gout are seen to be 40% lower with 4–5 cups of coffee a day. 1500 mg/day of vitamin C, in a supplemental form, is associated with a 45% decreased risk for elevated blood uric acid. Growing research is accumulating in the role of cherries, with their high vitamin C content, in the management of gout. Eating two servings of cherries a day is seen to significantly reduce blood uric acid, inflammation, and the number of gout attacks. There has been positive results with tart cherry juice concentrate in several small studies for the management of gout, but currently more research is needed to strengthen the validity of this treatment option. Purine-rich vegetables, nuts, legumes, and vegetable protein, despite their purine content, are not associated with gout. Furthermore, people who eat more vegetable protein have a 27% lower risk for developing gout.
So how can you take this information and apply it to yourself? First things first, you’ll have to reduce things that are seen to elevate blood uric acid. Try to reduce (or eliminate) meat (especially red meat), alcohol (beer and liquor, wine can stay!), and sugary foods. Reducing fish consumption may also be a good idea but the heart protective components of fish should be considered (especially since gout increases risks for heart disease). A DHA based omega-3 supplement should be strongly considered, especially if you are to remove fish. And now, what to add…. Exercise! If you’ve previously led a very sedentary lifestyle, start small. Find something you enjoy so that you’ll stick to it. Enrolling in a fitness class or finding a workout buddy is also another way to keep motivated. Most colleges have lots of fun workout classes—my personal favorite is aquafit! Eat more vegetables, nuts, cherries, and legumes and keep on drinking your coffee. Vitamin C supplements may also be a good addition. If you have gout and have had little relief from medical treatment, a tart cherry juice concentrate may be something good to try.
And that marks the end of my article, hopefully you now have a better idea of how to prevent and manage gout!
- See more at: http://www.sunwarrior.com/news/gout-a-growing-concern/#sthash.HxP6vFh7.dpuf


Gout: A Growing Concern

Friday, March 15, 2013 @ 05:03 AM Jennifer Novakovich
5.00/5 (100.00%) 1 vote
by Jennifer Novakovich
gout_a_growing_concern_imageGout is the most common form of arthritis in men over the age of 40 and was reported, in 2008, to affect over 8.3 million people in the United States. It is likely one of the oldest diseases and has even been observed in dinosaur bones. But it was first recognized by the Egyptians in 2640 BC. The disease is characterized by reoccurring episodes of extremely painful joint inflammation, caused by monosodium urate crystal deposits. Do you or someone you know have gout? Or are you concerned about developing gout in the future? Read on for more information about this painful disease.
Gout has markedly increased over the past few decades in parallel to the rise in obesity. In fact, more than 60% of individuals with gout have or later develop metabolic syndrome. Elevated uric acid levels, a precursor for gout, are associated with many other chronic diseases including diabetes, heart disease, hypertension, renal dysfunction, and obesity. For every 1mg of blood urate that is increased, there is a 13% heightened risk for hypertension!
Like I said before, higher levels of blood uric acid is a precursor for gout. So what is uric acid? Uric acid is a waste product of purines (e.g. adenosine, adenine, guanine) in the body following metabolism; it is our main fat soluble antioxidant, responsible for as much as two-thirds of our total antioxidant capacity. While short term increases in blood uric acid provide protection against oxidative stress, long term increases are associated with not only gout, but most chronic diseases. 
sugary_soft_drinks_increase_risk_for_gout_picAgain, increased blood uric acid content is thought to be an attempt for protection against oxidative stress. Risk factors for higher uric acid include a higher weight and body fat percentage with lower muscle mass as well as the consumption of meat (especially red meat), seafood, aspirin, diuretics, alcohol and sugary foods. Drinking alcohol, at intakes higher than 15g/day, results in a 93% higher risk of gout. Risks are significantly raised by drinking as little as 10-14.9g/day. Beer has been associated with 2.5 times higher risk while liquor is 1.6 times higher (risks don’t seem to be elevated through red wine consumption). Every additional meat serving per day leads to a 21% higher risk while seafood leads to a 7% higher risk. Lastly, daily consumption of sugary soft drinks increases risks for gout by 85%.
Most people with elevated blood uric acid never end up with gout, but for those who do, it usually happens by around 40–60 years of age in men and 65 in women. Males are over twice as likely to develop gout than females. Heightened uric acid in the blood can eventually lead to the formation of monosodium urate crystals, which are deposited in tissue. Eventually those deposits can lead to first acute gout—with little to no symptoms between gout attacks—and then, when not adequately treated, chronic gout—with symptoms between attacks and the formation of painful deformities. Acute gout usually begins in one joint in a lower limb and an attack results in a red, warm, swollen, and extremely painful joint. Gout is often a debilitating disease that significantly reduces the quality of life for those affected.
The goal in gout treatment is to lower blood urate levels and to dissolve urate crystals. Traditionally, on a pharmacological basis, acute gout is often managed with nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine, or glucocorticosteroids, while chronic gout is managed with urate-lowering therapy such as allopurinol, febuxostat, probenecid and sulfinpyrazone. Unfortunately for many, medical treatment for gout is often insufficient, and as a result individuals affected have little to no relief from gout symptoms and the development of the disease to chronic gout. Lifestyle interventions are an important component for the management of gout but unfortunately due to many factors (i.e. many doctors have little to no background in nutrition), patients are often not exposed to these recommendations.
cherries_reduce_blood_uric_acid_levels_imageWhat lifestyle interventions help manage gout? Exercise, weight loss, and also higher vegetable, nut, legume, coffee, and vitamin C consumption is associated with lower blood uric acid. Risks for gout are seen to be 40% lower with 4–5 cups of coffee a day. 1500 mg/day of vitamin C, in a supplemental form, is associated with a 45% decreased risk for elevated blood uric acid. Growing research is accumulating in the role of cherries, with their high vitamin C content, in the management of gout. Eating two servings of cherries a day is seen to significantly reduce blood uric acid, inflammation, and the number of gout attacks. There has been positive results with tart cherry juice concentrate in several small studies for the management of gout, but currently more research is needed to strengthen the validity of this treatment option. Purine-rich vegetables, nuts, legumes, and vegetable protein, despite their purine content, are not associated with gout. Furthermore, people who eat more vegetable protein have a 27% lower risk for developing gout.
So how can you take this information and apply it to yourself? First things first, you’ll have to reduce things that are seen to elevate blood uric acid. Try to reduce (or eliminate) meat (especially red meat), alcohol (beer and liquor, wine can stay!), and sugary foods. Reducing fish consumption may also be a good idea but the heart protective components of fish should be considered (especially since gout increases risks for heart disease). A DHA based omega-3 supplement should be strongly considered, especially if you are to remove fish. And now, what to add…. Exercise! If you’ve previously led a very sedentary lifestyle, start small. Find something you enjoy so that you’ll stick to it. Enrolling in a fitness class or finding a workout buddy is also another way to keep motivated. Most colleges have lots of fun workout classes—my personal favorite is aquafit! Eat more vegetables, nuts, cherries, and legumes and keep on drinking your coffee. Vitamin C supplements may also be a good addition. If you have gout and have had little relief from medical treatment, a tart cherry juice concentrate may be something good to try.
And that marks the end of my article, hopefully you now have a better idea of how to prevent and manage gout!
- See more at: http://www.sunwarrior.com/news/gout-a-growing-concern/#sthash.HxP6vFh7.dpuf

0 comments:

Post a Comment